2022

Cooles, F.A., Tarn, J., Lendrem, D.W., Naamane, N., Lin, C.M., Millar, B., Maney, N.J., Anderson, A.E., Thalayasingam, N., Diboll, J. and Bondet, V., Duffy D., Barnes M.R., Smith G.R., Ng S., Watson D., Henkin R., Cope A.P., Reynard L.N., Pratt A.G., Isaacs J.D., and the RA-MAP Consortium. Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming. Annals of the Rheumatic Diseases 81:1214-1223, 2022 DOI:

Banda, Nirmal K; Deane, Kevin D; Bemis, Elizabeth A; Strickland, Colin; Seifert, Jennifer; Jordan, Kimberly; Goldmann, Katriona; Morgan, B Paul; Moreland, Larry W; Lewis, Myles J.; Pitzalis, Costantino; Holers, V. Michael. Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features. The Journal of Immunology 208:11 2482-2496, 2022. DOI: 10.4049/jimmunol.2101170

Rivellese, Felice; Surace, Anna EA; Goldmann, Katriona; Sciacca, Elisabetta; Çubuk, Cankut; Giorli, Giovanni; John, Christopher R; Nerviani, Alessandra; Fossati-Jimack, Liliane; Thorborn, Georgina; … Lewis, Myles J; Pitzalis, Costantino Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial. Nature medicine 28NA1256-1268, 2022. DOI: 10.1038/s41591-022-01789-0

Sciacca, E; Surace, A; Alaimo, S; Pulvirenti, A; Rivellese, F; Goldmann, K; Ferro, A; Latora, V; Pitzalis, C; Lewis, M; ... Network analysis of synovial RNA sequencing identifies gene-gene interactions predictive of response in rheumatoid arthritis. Arthritis Research & Therapy 24:166, 2022. DOI: 10.1186/s13075-022-02803-z

McLeod, Graeme; Kennedy, Iain; Simpson, Eilidh; Joss, Judith; Goldmann, Katriona. Pilot Project for a Web-Based Dynamic Nomogram to Predict Survival 1 Year After Hip Fracture Surgery: Retrospective Observational Study. Interactive Journal of Medical Research 11: 1 e34096, 2022. DOI: 10.2196/34096

Micheroli, Raphael; Elhai, Muriel; Edalat, Sam; Frank-Bertoncelj, Mojca; Bürki, Kristina; Ciurea, Adrian; MacDonald, Lucy; Kurowska-Stolarska, Mariola; Lewis, Myles J; Goldmann, Katriona, Cubuk, Cankut; Kuret, Tadeja; Distler, Oliver; Pitzalis, Costantino; Ospelt, Caroline. Role of synovial fibroblast subsets across synovial pathotypes in rheumatoid arthritis: a deconvolution analysis. RMD open 8: 1 e001949, 2022. DOI: 10.1136/rmdopen-2021-001949

2021

Boutet, Marie-Astrid; Nerviani, Alessandra; Lliso-Ribera, Gloria; Leone, Roberto; Sironi, Marina; Hands, Rebecca; Rivellese, Felice; Del Prete, Annalisa; Goldmann, Katriona; Lewis, Myles J; … Pitzalis, Costantino Circulating and synovial pentraxin-3 (PTX3) expression levels correlate with rheumatoid arthritis severity and tissue infiltration independently of conventional treatments response. Frontiers in immunology 12NA2512, 2021. DOI: 10.3389/fimmu.2021.686795

Nerviani, Alessandra; Boutet, Marie-Astrid; Tan, Wang Sin Gina; Goldmann, Katriona; Purkayastha, Nirupam; Lajtos, Tamas Ajtos; Hands, Rebecca; Lewis, Myles; Kelly, Stephen; Pitzalis, Costantino. IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors. Annals of the rheumatic diseases 80: 5 591-597, 2021. DOI: 10.1136/annrheumdis-2020-218186

Rivellese, Felice; Manou-Stathopoulou, Sotiria; Mauro, Daniele; Goldmann, Katriona; Pyne, Debasish; Rajakariar, Ravindra; Gordon, Patrick; Schafer, Peter; Bombardieri, Michele; Pitzalis, Costantino. Effects of targeting the transcription factors Ikaros and Aiolos on B cell activation and differentiation in systemic lupus erythematosus. Lupus science & medicine 8: 1 e000445, 2021. DOI: 10.1136/lupus-2020-000445

Hosseini, Kasra; Coll Ardanuy, Mariona; Patterson, David; Garcia-Velez, Laura; Castro-Gonzalez, Leonardo; Deecke, Lucas; Nielsen, Dan; Cho, Selina; Dwyer, Lesely; Auyeung, Victoria; … Goldmann, Katriona. Data Study Group Final Report: Smart monitoring for conservation areas. WWF and Alan Turing Institute Data Study Group Report, 2020. DOI: 10.5281/zenodo.3878457

Cherlin, Svetlana; Lewis, Myles J; Plant, Darren; Nair, Nisha; Goldmann, Katriona; Tzanis, Evan; Barnes, Michael R; McKeigue, Paul; Barrett, Jennifer H; Pitzalis, Costantino; ... Cordell, Heather. Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response. Annals of the rheumatic diseases 79:11 1446-1452, 2020. DOI: 10.1136/annrheumdis-2020-217204

Rivellese, Felice; Humby, F; Bugatti, S; Fossati-Jimack, L; Rizvi, H; Lucchesi, D; Lliso‐Ribera, G; Nerviani, A; Hands, RE; Giorli, G.; Frias, B; Thorborn, G; Jaworska, E; John, C; Goldmann, K; Lewis, M. J.; Manzo, A.; Bombardieri, M.; Pitzalis, C.; the PEAC-R4RA Investigators. B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure. Arthritis & Rheumatology 72: 5 714-725, 2020. DOI: 10.1002/art.41184

Boutet, Marie-Astrid; Nerviani, Alessandra; Lliso-Ribera, Gloria; Lucchesi, Davide; Prediletto, Edoardo; Ghirardi, Giulia Maria; Goldmann, Katriona; Lewis, Myles; Pitzalis, Costantino. Interleukin-36 family dysregulation drives joint inflammation and therapy response in psoriatic arthritis. Rheumatology 59: 4 828-838, 2020. DOI: 10.1093/rheumatology/kez358

John, Christopher R; Watson, David; Russ, Dominic; Goldmann, Katriona; Ehrenstein, Michael; Pitzalis, Costantino; Lewis, Myles; Barnes, Michael. M3C: Monte Carlo reference-based consensus clustering. Scientific reports 10: 1 Jan-14, 2020. DOI: 10.1038/s41598-020-58766-1

Pucino, Valentina; Certo, Michelangelo; Bulusu, Vinay; Cucchi, Danilo; Goldmann, Katriona; Pontarini, Elena; Haas, Robert; Smith, Joanne; Headland, Sarah E; Blighe, Kevin; … Pitzalis, Costantino; Mauro, Claudio. Lactate buildup at the site of chronic inflammation promotes disease by inducing CD4+ T cell metabolic rewiring. Cell metabolism 30: 6 1055-1074. e8, 2019. DOI: 10.1016/j.cmet.2019.10.004

Lewis, Myles J; Barnes, Michael R; Blighe, Kevin; Goldmann, Katriona; Rana, Sharmila; Hackney, Jason A; Ramamoorthi, Nandhini; John, Christopher R; Watson, David S; Kummerfeld, Sarah K; … Pitzalis, Costantino. Molecular portraits of early rheumatoid arthritis identify clinical and treatment response phenotypes. Cell reports 28: 9 2455-2470. e5, 2019. DOI: 10.1016/j.celrep.2019.07.091

El Shikh, Mohey Eldin M; El Sayed, Riham; Nerviani, Alessandra; Goldmann, Katriona; John, Christopher Robert; Hands, Rebecca; Fossati-Jimack, Liliane; Lewis, Myles J; Pitzalis, Costantino. Extracellular traps and PAD4 released by macrophages induce citrullination and auto-antibody production in autoimmune arthritis. Journal of Autoimmunity 105NA102297, 2019. DOI: 10.1016/j.jaut.2019.06.008

Cope, Andrew P; Barnes, Michael R; Belson, Alexandra; Binks, Michael; Brockbank, Sarah; Bonachela-Capdevila, Francisco; Carini, Claudio; Fisher, Benjamin A; Goodyear, Carl S; Emery, Paul. & the RA-MAP consortium. The RA-MAP Consortium: a working model for academia–industry collaboration. Nature Reviews Rheumatology 14: 1 53-60, 2018. DOI: 10.1038/nrrheum.2017.200